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Volltext Gengenbach_Thomas.pdf1.pdf (6,8 MB)
URN (für Zitat) http://nbn-resolving.org/urn:nbn:de:swb:90-287959
Titel Numerical Simulation of Particle Deposition in the Human Lungs
Autor Gengenbach, Thomas
Institution Institut für Angewandte und Numerische Mathematik (IANM)
Dokumenttyp Buch
Verlag Karlsruhe
Jahr 2012
Hochschulschrift Dissertation
Fakultät für Mathematik (MATH)
Institut für Angewandte und Numerische Mathematik (IANM)
Prüfungsdaten: 27.06.2012
Referent/Betreuer: Prof. V. Heuveline
Abstract We model, simulate and calculate breathing and particle depositions in the human lungs. We review the theory and discretization of fluid mechanics, the anatomy, physiology and measuring methods of lungs. A new model is introduced and investigated with a sensitivity analysis using the singular value decomposition. Particle depositions are simulated in patient-specific and schematized human lungs and compared to the particle deposition in a multiplicative model of subsequent bifurcations.